Details here:
https://support.microsoft.com/en-us/topic/managing-deployment-of-printer-rpc-binding-changes-for-cve-2021-1678-kb4599464-12a69652-30b9-3d61-d9f7-7201623a8b25
Tested with Server Cumulative Update December 2021.
Disable print spooler on all servers where it is unnecessary.
Push out Point and Print settings to all machines via GPO (change FQDNs and add another other print servers or clients hosting printers for your environment):
Make sure "Do not show warning or elevation prompt" is enabled on the Point and Print Restrictions policy.
On the client and print server enable Enforcement Mode:
HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\Print
Right-click Print, choose New, and then click DWORD VALUE (32-bit) Value.
Type RpcAuthnLevelPrivacyEnabled and then press Enter.
Right-click RpcAuthnLevelPrivacyEnabled and then click Modify.
In the Value data box, type 1 and then click Ok.
If you have trouble printing, try setting the above value to 0 however, you are less protected from PrintNightmare in this case.